Severe combined immunodeficiencies (SCID)

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منابع مشابه

Early Diagnosis of Severe Combined Immunodeficiencies

aDirector of Research, Israelita Albert Einstein Hospital, São Paulo, SP, Brasil. Received on January 11, 2017. © 2017 Sociedade de Pediatria de São Paulo. Published by Zeppelini Publishers. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). EARLY DIAGNOSIS OF SEVERE COMBINED IMMUNODEFICIENCIES Diagnóstico precoce das imunodeficiências combinad...

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Newborn screening for severe combined immunodeficiency (SCID): a review.

Because prompt intervention may prevent complications, early diagnosis is important in many inherited metabolic diseases. Early diagnosis of Severe Combined Immunodeficiency (SCID) is critical - because chances for successful treatment are highest for infants who have not yet experienced severe opportunistic infections. SCID is a rare disease that can be detected in newborn infants (i.e., those...

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Adriamycin nephropathy in severe combined immunodeficient (SCID) mice.

Experimental focal glomerulosclerosis is a model of chronic proteinuric renal disease that has been induced in both rats and mice. In mice, the adriamycin (ADR)induced nephropathy model is a robust experimental analogue of human focal glomerulosclerosis [1]. Renal injury in the ADR-induced nephropathy model is characterized by changes in both the tubulointerstitial and glomerular compartments. ...

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Thymic epithelial cells of severe combined immunodeficiency (SCID) mice.

To characterize thymic epithelial cells of SCID (severe combined immunodeficiency) mice in comparison with those of Balb C mice, we did an immunohistochemical study using cortical and medullary epithelial cell specific monoclonal antibodies (MoAbs), Th-3 and Th-4, as well as gel electrophoresis and immunoblotting. The thymi of SCID mice were composed of epithelial cells and a few lymphocytes. M...

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Severe viral infections and primary immunodeficiencies.

Patients with severe viral infections are often not thoroughly evaluated for immunodeficiencies. In this review, we summarize primary immunodeficiencies that predispose individuals to severe viral infections. Some immunodeficiencies enhance susceptibility to disease with a specific virus or family of viruses, whereas others predispose to diseases with multiple viruses in addition to disease wit...

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ژورنال

عنوان ژورنال: Clinical & Experimental Immunology

سال: 2000

ISSN: 0009-9104

DOI: 10.1046/j.1365-2249.2000.01359.x